Comparison of three different protocols of alkaloid extraction from Glaucium corniculatum plant

Alkaloids, plant secondary metabolites, have a wide variety of biological effects. For this reason, the extraction alkaloids from plants is strategic importance. Different protocols for been described by many authors. The objective study was to compare efficacy three different Glaucium corniculatum. This article compares Soxhlet and ultrasonication protocol, used in previous studies, modified protocol. While alkaloid amount extract determined spectrophotometric method, qualitative estimation compounds Gas chromatograph-Mass spectrometer (GC-MS). diversity extract, obtained through recommended were higher than that any other protocols. Thus, new protocol established, which better